Matasi, Julius: search on Z-Library

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1

Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors

Seganish, W. Michael, Fischmann, Thierry O., Sherborne, Brad, Matasi, Julius, Lavey, Brian, McElroy, William T., Tulshian, Deen, Tata, James, Sondey, Christopher, Garlisi, Charles G., Devito, Kristine

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 5.27 MB

english, 2015

2

Hydrogenation of vinylogous esters

James W. Herndon, Julius J. Matasi

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 265 KB

english, 1992

3

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine Analogues as Adenosine A2A Antagonists: The Successful Reduction of hERG Activity. Part 2.

Julius J. Matasi, John P. Caldwell, Hongtao Zhang, Ahmad Fawzi, Guy A. Higgins, Mary E. Cohen-Williams, Geoffrey B. Varty, Deen B. Tulshian

Journal:

Year:

2006

File:

PDF, 12 KB

2006

4

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs: Highly potent, orally active, adenosine A2A antagonists. Part 1

Julius J. Matasi, John P. Caldwell, Hongtao Zhang, Ahmad Fawzi, Mary E. Cohen-Williams, Geoffrey B. Varty, Deen B. Tulshian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 170 KB

english, 2005

5

Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: Part 2

Stephanie Brumfield, Julius J. Matasi, Deen Tulshian, Michael Czarniecki, William Greenlee, Charles Garlisi, Hongchen Qiu, Kristine Devito, Shu-Cheng Chen, Yongliang Sun, Rosalia Bertorelli, Justin An

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 470 KB

english, 2011

6

Rhodium(II) catalyzed intramolecular reactions between vinyldiazomethanes and pyrroles. Novel synthesis of fused 7-azabicyclo[4.2.0]octadienes

Huw M.L. Davies, Julius J. Matasi

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 289 KB

english, 1994

7

Divergent Pathways in the Intramolecular Reactions between Rhodium-Stabilized Vinylcarbenoids and Pyrroles: Construction of Fused Tropanes and 7-Azabicyclo[4.2.0]octadienes

Davies, Huw M. L., Matasi, Julius J., Ahmed, Gulzar

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 480 KB

english, 1996

8

Intramolecular coupling of conjugated enynes with cyclopropylcarbene–chromium complexes; a complex reaction pathway

Julius J Matasi, Jingbo Yan, James W Herndon

Journal:

Inorganica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 114 KB

english, 1999

9

Control of carbenoid reactivity through neighboring group participation

Huw M.L. Davies, Julius J. Matasi, Craig Thornley

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 195 KB

english, 1995

10

Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: Part 1

Julius J. Matasi, Stephanie Brumfield, Deen Tulshian, Michael Czarnecki, William Greenlee, Charles G. Garlisi, Hongchen Qiu, Kristine Devito, Shu-Cheng Chen, Youngliang Sun, Rosalia Bertorelli, Willia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

11

Absolute configuration of C27H41NO8Si, the diastereoselective product of the rhodium(II) octanoate catalyzed decomposition of a chiral vinyldiazomethane in the presence of 2-acetylpyrrole: A structural study rendered difficult by disorder of a “heavy” atom

Melvyn Rowen Churchill, David George Churchill, Julius J. Matasi, Huw M.L. Davies

Journal:

Journal of Chemical Crystallography

Year:

1999

Language:

english

File:

PDF, 102 KB

english, 1999

12

Reactions of Cyclopropylcarbene-Chromium Complexes

Herndon, James W., Tumer, Seniz U., McMullen, Leonard A., Matasi, Julius J., Schnatter, Wayne F. K., Daitch, Charles E.

Journal:

Comments on Inorganic Chemistry

Year:

1990

Language:

english

File:

PDF, 883 KB

english, 1990

13

Preparation of seven-membered rings by the reaction of cyclopropylcarbene-tungsten and molybdenum complexes with alkynes

James W. Herndon, Metin Zora, Paren P. Patel, Gautam Chatterjee, Julius J. Matasi, Seniz U. Tumer

Journal:

Year:

1993

Language:

english

File:

PDF, 1.39 MB

english, 1993

14

Synthesis of 3β-Aryl-8-azabicyclo[3.2.1]octanes with High Binding Affinities and Selectivities for the Serotonin Transporter Site

Davies, Huw M. L., Kuhn, Lisa A., Thornley, Craig, Matasi, Julius J., Sexton, Tammy, Childers, Steven R.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 153 KB

english, 1996

15

Nociceptin inhibits capsaicin-induced bronchoconstriction in isolated guinea pig lung

Michel R Corboz, Maria A Rivelli, Robert W Egan, Deen Tulshian, Julius Matasi, Ahmad B Fawzi, Lawrence Benbow, April Smith-Torhan, Hongtao Zhang, John A Hey

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 139 KB

english, 2000

16

The Discovery and Synthesis of Novel Adenosine Receptor (A2A) Antagonists.

Julius J. Matasi, John P. Caldwell, Jinsong Hao, Bernard Neustadt, Leyla Arik, Carolyn J. Foster, Jean Lachowicz, Deen B. Tulshian

Journal:

Year:

2005

File:

PDF, 21 KB

2005

17

Alterations in behavior and opioid gene expression induced by the novel tropane analog WF-31

James B. Daunais, Stephanie L. Hart, Ashlee Hedgecock-Rowe, Julius J. Matasi, Craig Thornley, Huw M.L. Davies, Linda J. Porrino

Journal:

Molecular Brain Research

Year:

1997

Language:

english

File:

PDF, 1.17 MB

english, 1997

18

Bioavailable pyrrolo-benzo-1,4-diazines as Nav1.7 sodium channel blockers for the treatment of pain

Yang, Shu-Wei, Ho, Ginny D., Tulshian, Deen, Bercovici, Ana, Tan, Zheng, Hanisak, Jennifer, Brumfield, Stephanie, Matasi, Julius, Sun, Xianfeng, Sakwa, Samuel A., Herr, R. Jason, Zhou, Xiaoping, Brida

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.70 MB

english, 2014

19

The discovery and synthesis of novel adenosine receptor (A2A) antagonists

Julius J. Matasi, John P. Caldwell, Jinsong Hao, Bernard Neustadt, Leyla Arik, Carolyn J. Foster, Jean Lachowicz, Deen B. Tulshian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 122 KB

english, 2005

20

Synthesis of cyclopentane-fused oxygen heterocycles from the intramolecular reaction of alkynes with cyclopropylcarbene-chromium complexes

Herndon, James W., Matasi, Julius J.

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 941 KB

english, 1990

21

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine Analogues: Highly Potent, Orally Active, Adenosine A2A Antagonists. Part 1.

Julius J. Matasi, John P. Caldwell, Hongtao Zhang, Ahmad Fawzi, Mary E. Cohen-Williams, Geoffrey B. Varty, Deen B. Tulshian

Journal:

Year:

2006

File:

PDF, 22 KB

2006

22

Effect of carbenoid structure on the reactivity of rhodium-stabilized carbenoids

Huw M.L. Davies, L. Mark Hodges, Julius J. Matasi, Tore Hansen, Douglas G. Stafford

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 234 KB

english, 1998

23

Synthesis of 2.beta.-Acyl-3.beta.-aryl-8-azabicyclo[3.2.1]octanes and Their Binding Affinities at Dopamine and Serotonin Transport Sites in Rat Striatum and Frontal Cortex

Davies, Huw M. L., Saikali, Elie, Huby, Nicholas J. S., Gilliatt, Vernon J., Matasi, Julius J., Sexton, Tammy, Childers, Steven R.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.01 MB

english, 1994

24

Initial optimization and series evolution of diaminopyrimidine inhibitors of interleukin-1 receptor associated kinase 4

Seganish, W. Michael, McElroy, William T., Herr, R. Jason, Brumfield, Stephanie, Greenlee, William J., Harding, James, Komanduri, Venukrishnan, Matasi, Julius, Prakash, Koraboina Chandra, Tulshian, De

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 5.06 MB

english, 2015

25

Synthesis and structure–activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands

John P. Caldwell, Julius J. Matasi, Hongtao Zhang, Ahmad Fawzi, Deen B. Tulshian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 127 KB

english, 2007

26

Enantioselective Synthesis of Functionalized Tropanes by Rhodium(II) Carboxylate-Catalyzed Decomposition of Vinyldiazomethanes in the Presence of Pyrroles

Davies, Huw M. L., Matasi, Julius J., Hodges, L. Mark, Huby, Nicholas J. S., Thornley, Craig, Kong, Norman, Houser, Jeffrey H.

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 422 KB

english, 1997

27

Synthesis and structure–activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands: Part 2

John P. Caldwell, Julius J. Matasi, Xiomara Fernandez, Robbie L. McLeod, Hongtao Zhang, Ahmad Fawzi, Deen B. Tulshian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 699 KB

english, 2009

28

Cyclopropylcarbene-tungsten complexes + alkynes: a [4 + 2 + 1] cycloaddition route for the construction of seven-membered rings

Herndon, James W., Chatterjee, Gautam, Patel, Paren P., Matasi, Julius J., Tumer, Seniz U., Harp, Jill J., Reid, Margaret D.

Journal:

Journal of the American Chemical Society

Year:

1991

Language:

english

File:

PDF, 263 KB

english, 1991

29

Local cerebral metabolic effects of the novel cocaine analog, WF-31: Comparisons to fluoxetine

Linda J. Porrino, Mack Miller, Ashlee A. Hedgecock, Craig Thornley, Julius J. Matasi, Huw M.L. Davies

Journal:

Year:

1997

Language:

english

File:

PDF, 137 KB

english, 1997

30

ChemInform Abstract: Relative Asymmetric Induction in the Intramolecular Reaction Between Alkynes and Cyclopropylcarbene—Chromium Complexes: Stereocontrolled Synthesis of Five-Membered Rings Fused to Oxygen Heterocycles.

Jingbo Yan, Jin Zhu, Julius J. Matasi, James W. Herndon

Journal:

Year:

1999

File:

PDF, 38 KB

1999

31

Discovery of pyrrolo-benzo-1,4-diazines as potent Nav1.7 sodium channel blockers

Ho, Ginny D., Tulshian, Deen, Bercovici, Ana, Tan, Zheng, Hanisak, Jennifer, Brumfield, Stephanie, Matasi, Julius, Heap, Charles R., Earley, William G., Courneya, Brandy, Jason Herr, R., Zhou, Xiaopin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 901 KB

english, 2014

32

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs as adenosine A2A antagonists: The successful reduction of hERG activity. Part 2

Julius J. Matasi, John P. Caldwell, Hongtao Zhang, Ahmad Fawzi, Guy A. Higgins, Mary E. Cohen-Williams, Geoffrey B. Varty, Deen B. Tulshian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 161 KB

english, 2005

33

3H-[1,2,4]-Triazolo[5,1-i]purin-5-amine derivatives as adenosine A2A antagonists

Lisa S. Silverman, John P. Caldwell, William J. Greenlee, Eugenia Kiselgof, Julius J. Matasi, Deen B. Tulshian, Leyla Arik, Carolyn Foster, Rosalia Bertorelli, Angela Monopoli, Ennio Ongini

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

34

Structure–activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain

Shu-Wei Yang, Jennifer Smotryski, Julius Matasi, Ginny Ho, Deen Tulshian, William J. Greenlee, Rossella Brusa, Massimiliano Beltramo, Kathleen Cox

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.66 MB

english, 2011

35

Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain

Brumfield, Stephanie, Korakas, Peter, Silverman, Lisa S., Tulshian, Deen, Matasi, Julius J., Qiang, Li, Bennett, Chad E., Burnett, Duane A., Greenlee, William J., Knutson, Chad E., Wu, Wen-Lian, Sasik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 3.62 MB

english, 2012

36

GLASGOW SOUTHERN MEDICAL SOCIETY.

Brumfield, Stephanie, Korakas, Peter, Silverman, Lisa S., Tulshian, Deen, Matasi, Julius J., Qiang, Li, Bennett, Chad E., Burnett, Duane A., Greenlee, William J., Knutson, Chad E., Wu, Wen-Lian, Sasik

Journal:

Year:

1900

Language:

english

File:

PDF, 1.03 MB

english, 1900

37

Relative Asymmetric Induction in the Intramolecular Reaction between Alkynes and Cyclopropylcarbene−Chromium Complexes: Stereocontrolled Synthesis of Five-Membered Rings Fused to Oxygen Heterocycles

Yan, Jingbo, Zhu, Jin, Matasi, Julius J., Herndon, James W.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 150 KB

english, 1999

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